Article
Th1/Th2 Balance and Th17/Treg-Mediated Immunity in relation to Murine Resistance to Dextran Sulfate-Induced Colitis.
Journal of immunology research - 1 Jan 2017
Yang Fangli, Wang Danan, Li Yan, Sang Lixuan, Zhu Junfeng, Wang Jinyan, Wei Bing, Lu Changlong, Sun Xun
Abstract excerpt
BACKGROUND: The role of the Th17/Treg balance in the development of experimental colitis remains poorly understood. METHODS: We exploited the differential response of BALB/c mice and C57BL/6 mice towards drinking water mediated by dextran sulfate sodium (DSS) challenge. RESULTS: DSS-resistant BALB/c mice were characterized by low levels of IFN-γ and TNF-α but high levels of IL-4, IL-6, IL-10, IL-17A, IL-17F, and...
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