Article
Differential susceptibility of inbred mouse strains to Helicobacter pylori infection.
Scandinavian journal of gastroenterology - 1 Mar 2002
Mähler M, Janke C, Wagner S, Hedrich H J
Abstract excerpt
BACKGROUND: Host factors play an important part in the pathogenesis of Helicobacter pylori-associated disease. The aim of this study was to screen various inbred strains of mice for genetic differences in susceptibility to H. pylori infection. METHODS: Mice of strains BALB/cJ, C.B-17-Prkdc(scid), C3H/HeJ, C3H/HeN, C57BL/6J, C57BL/6J-I110(tm/Cgn), DBA/2J, and FVB/N were inoculated intragastrically with H. pylori...
Topics
- Animals
- Base Sequence
- Colony Count, Microbial
- DNA, Bacterial
- Disease Models, Animal
- Female
- Gastric Mucosa
- Gastritis
- Genetic Predisposition to Disease
- Helicobacter Infections
- Helicobacter pylori
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Molecular Sequence Data
- Polymerase Chain Reaction
