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Sex and strain dependent differences in mucosal immunology and microbiota composition in mice

18 Jun 2018

Abstract excerpt

BACKGROUND: A dysbiosis in the intestinal microbiome plays a role in the pathogenesis of several immunological diseases. These diseases often show a sex bias, suggesting sex differences in immune responses and in the intestinal microbiome. We hypothesized that sex differences in immune responses are associated with sex differences in microbiota composition. METHODS: Fecal microbiota composition (MITchip), mRNA...

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PMID: 29914546
DOI: 10.1186/s13293-018-0186-6

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