Article
A tumor necrosis factor-alpha (TNF-alpha) promoter polymorphism is associated with chronic hepatitis B infection.
Clinical and experimental immunology - 1 Mar 1998
Höhler T, Kruger A, Gerken G, Schneider P M, Meyer zum Büschenefelde K H, Rittner C
Abstract excerpt
Cytokines such as TNF-alpha and interferon gamma (IFN-gamma) are important for the elimination of infected hepatocytes during acute hepatitis B virus (HBV) infection. Two G versus A transitions in the TNF-alpha promoter region at positions -308 and -238 possibly influence TNF-alpha expression. We...
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