Article
TNF-alpha promoter region polymorphisms affect HBV virus clearance in southern Chinese.
Clinica chimica acta; international journal of clinical chemistry - 21 Oct 2013
Xu Jianhua, Zhang Sanjiao, Zhang Zhaofeng, Fu Lingyuan, Zheng Qiupeng, Wang Jian, Lu Shengzhen, Du Jing
Abstract excerpt
BACKGROUND: There are many cytokines, including TNF-α, TGFβ, PGF, and other factors contributing towards fibrogenesis, that play a role in the control of HBV infection. Among these, TNF-α is the most important cytokine in host immune response to viral infection. This study aimed to determine whether differences in the promoter region of the TNF-α gene may alter the outcomes of HBV infection. METHODS: Two...
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