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Article

Tumor necrosis factor-alpha-308A allele may have a protective effect for chronic hepatitis B virus infection in Mongoloid populations.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jul 2010

Zheng Ming-Hua, Qiu Li-Xin, Xin Yong-Ning, Pan Hai-Feng, Shi Ke-Qing, Chen Yong-Ping

Abstract excerpt

OBJECTIVES: Previous studies on the tumor necrosis factor-alpha (TNF-alpha)-308 gene promoter polymorphism in chronic hepatitis B virus (HBV) infection have reported conflicting results. METHODS: We carried out a meta-analysis of 21 studies in relation to the TNF-alpha-308 gene promoter, involving a total of 4230 chronic HBV infection cases and 2905 controls. RESULTS: The overall meta-analysis indicated that...

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Asian People
Case-Control Studies
Gene Frequency
Hepatitis B, Chronic
Hepatitis B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Tumor Necrosis Factor-alpha

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PMID: 20004605
DOI: 10.1016/j.ijid.2009.08.010

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TNF

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