Article
Associations of tumour necrosis factor alpha promoter polymorphisms at position -308 and -238 with clinical characteristics of chronic hepatitis C.
Journal of viral hepatitis - 1 Nov 2006
Dai C-Y, Chuang W-L, Lee L-P, Chen S-C, Hou N-J, Lin Z-Y, Hsieh M-Y, Hsieh M-Y, Wang L-Y, Chang W-Y, Yu M-L
Abstract excerpt
The aim of this study was to investigate the association between G vs A transitions in the promoter region of the tumour necrosis factor (TNF) alpha at positions -308 (TNF308.2) and -238 (TNF238.2) and clinical features of chronic hepatitis C (CHC). These two promoter TNF-alpha variants were determined in 250 biopsy-proven CHC patients by polymerase chain reaction amplification, followed by the Restriction...
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