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Article

Tumor necrosis factor-alpha gene promoter polymorphism in Iranian patients with chronic hepatitis B.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Jan 2000

Somi M H, Najafi L, Noori B N, Alizadeh A H M, Aghah M R, Shavakhi A, Ehsani M J, Aghazadeh R, Masoodi M, Amini S, Baladast M, Zali M R

Abstract excerpt

BACKGROUND: Clearance of hepatitis B virus (HBV) infection requires a good host immune response. Cytokines like tumor necrosis factor-alpha (TNF- alpha) may play a role in such immune response. Genetic changes in TNF-a gene promoter region are known to influence TNF- alpha expression. We therefore studied the role of one such mutation in chronic HBV infection. METHODS: Presence of -308 G/A polymorphism in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16567888

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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