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Article

Tumor necrosis factor gene polymorphisms and clearance or progression of hepatitis B virus infection.

Liver international : official journal of the International Association for the Study of the Liver - 1 Dec 2005

Niro Grazia Anna, Fontana Rosanna, Gioffreda Domenica, Valvano Maria Rosa, Lacobellis Angelo, Facciorusso Domenico, Andriulli Angelo

Abstract excerpt

OBJECTIVES: We evaluated the influence of tumor necrosis factor-alpha (TNF-alpha) promoter gene polymorphisms on clearance of hepatitis B virus (HBV) and outcome of HBV chronic hepatitis. METHODS: Four TNF-alpha promoter polymorphisms (T-1031C, C-863A, G-308A, and G-238A) were evaluated by direct sequencing in 184 chronic HBV carriers hepatitis B surface antigen (HBsAg) positive and 96 controls with documented...

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Source

Identifiers

PMID: 16343069
DOI: 10.1111/j.1478-3231.2005.01166.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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