Article
Clinical correlations with allelotype in supraglottic squamous cancer.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Mar 1998
Scholnick S B, El-Mofty S K, Shaw M E, Sunwoo J B, Haughey B H, Sun P C, Piccirillo J F, Zequeira M R
Abstract excerpt
Frequent allelic loss at a genetically polymorphic locus in tumors is an established marker for the presence of a tumor suppressor gene in the neighboring chromosomal region. This technique can be used to identify novel tumor suppressor genes and to monitor their status before the cloning of the...
Topics
- Alleles
- Carcinoma, Squamous Cell
- Genes, Tumor Suppressor
- Glottis
- Humans
- Laryngeal Neoplasms
- Microsatellite Repeats
- Neoplasm Recurrence, Local
- Neoplasm Staging
- Prognosis
- Statistics as Topic