Article
Genomic instability in squamous cell carcinoma of the head and neck.
Anticancer research - 1 Jan 2000
Field J K
Abstract excerpt
The role of genomic instability in the development of squamous cell carcinoma (SCCHN) has become apparent with the publication of three major allelotype analysis of this disease, as well as many publications which have concentrated on specific target regions. The measurement of accumulated genetic alterations or fractional allele loss, as determined by allelotype analysis, provides a useful molecular indicator of...
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