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Article

Critical role of R-loops in processing replication blocks.

Frontiers in bioscience : a journal and virtual library - 1 Jan 2005

Camps Manel, Loeb Lawrence A

Abstract excerpt

Blocks in replication result from impediments to the advancing replication machinery and are lethal if not resolved. The replication fork must be reassembled for DNA synthesis to proceed. Fork assembly outside the chromosomal origin of replication (oriC) is mediated by recombination or via a helicase-dependent pathway. ColE1 plasmid origins of replication and oriK sites initiate primosome assembly by an RNA-DNA...

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Identifiers

PMID: 15569610
DOI: 10.2741/1564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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