Article
Tel Aviv-Heidelberg three-generation offspring study: genetic determinants of apolipoprotein A1 and apolipoprotein B.
American journal of medical genetics - 3 Jul 1995
Livshits G, Blettner M, Graff E, Hoting I, Wahrendorf J, Brunner D, Schettler G
Abstract excerpt
The contribution of major gene and multifactorial effects on variation of plasma apolipoproteins A1 and B has been tested in a large sample of population-based Israeli pedigrees. Our most parsimonious and best fitting model for both apolipoproteins is consistent with Mendelian transmissibility, with significant contribution of major genes (with 2 alleles recessive and dominant within each locus) and polygenes,...
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