Article
Lipoprotein(a): identification of subjects with a superbinding capacity for fibrinogen.
Clinical genetics - 1 Nov 1997
Scanu A M, Atzeni M M, Edelstein C, Tonolo G, Maioli M, Klezovitch O
Abstract excerpt
We have previously shown that the binding of lipoprotein(a) [Lp(a)] to immobilized fibrinogen involves the domain located in kringles IV-5 to IV-8, but not kringle IV-10. In extending those studies to subjects living in Chicago and in the island of Sardinia, we found that about 6% of them had an Lp(a) with Bmax values of 27.7+/-6.0 fmol, which were about 5-8-fold higher than those of controls (3.4+/-2.8 fmol) and...
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