Article
Amplification of human APO(a) kringle 4-37 from blood lymphocyte DNA.
Biochimica et biophysica acta - 25 Nov 1993
Pfaffinger D, Mc Lean J, Scanu A M
Abstract excerpt
We have been able to amplify the lysine binding pocket region of human apo(a) kringle type 5 starting from the DNA isolated from peripheral blood lymphocytes. This development now permits the identification of Lp(a) mutants that by lacking their ability to bind to lysine/fibrin would have a lesse...
Topics
- Amino Acid Sequence
- Apolipoproteins A
- Base Sequence
- DNA
- Humans
- Kringles
- Lymphocytes
- Lysine
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Amplification Techniques
