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Article

The identification and significance of a Thr-->Pro polymorphism in kringle IV type 8 of apolipoprotein(a).

Thrombosis and haemostasis - 1 May 1997

Prins J, Leus F R, van der Hoek Y Y, Kastelein J J, Bouma B N, van Rijn H J

Abstract excerpt

Elevated plasma levels of lipoprotein(a) [Lp(a)] represent a significant independent risk factor for the development of atherosclerosis. Interindividual levels of apo(a) vary over 1000-fold and are mainly due to inheritance that is linked to the locus of the apolipoprotein(a) [apo(a)] gene. The apo(a) gene encodes multiple repeats of a sequence exhibiting up to 85% DNA sequence homology with plasminogen kringle...

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PMID: 9184408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The identification and significance of a Thr-->Pro polymorphism in kringle IV type 8 of apolipoprotein(a).PMID 9184408Read ↗

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