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Article

Apolipoprotein(a): structural and functional consequences of mutations in kringle type 10 (or kringle 4-37).

Clinical genetics - 1 Jul 1994

Scanu A M, Edelstein C

Abstract excerpt

The size polymorphism of Lp(a) is well recognized. It is now apparent that there is an additional polymorphism resulting from mutations occurring at the kringle level. One of these mutations involves a trp72 to arg substitution in apo(a) kringle type 10 and is attended by a defective binding of Lp(a) to immobilized lysine/fibrin. Other mutations affecting the other amino acids of the "lysine-binding pocket" may...

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Source

Identifiers

PMID: 7988076
DOI: 10.1111/j.1399-0004.1994.tb04200.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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