Article
Adenosine A1 receptor and bipolar affective disorder: systematic screening of the gene and association studies.
American journal of medical genetics - 7 Feb 1998
Deckert J, Nöthen M M, Albus M, Franzek E, Rietschel M, Ren H, Stiles G L, Knapp M, Weigelt B, Maier W, Beckmann H, Propping P
Abstract excerpt
In the present study we sought to identify genetic variation in the adenosine A1 receptor (A1AR) gene on chromosome 1q31-32.1, which through alteration of protein function or level of expression might contribute to the genetic predisposition to bipolar affective disorder. We performed a systematic mutation scan of the whole coding sequence as well as 5' and 3' untranslated regions by means of single-strand...
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