Article
Human adenosine A1 receptor gene: systematic screening for DNA sequence variation and linkage mapping on chromosome 1q31-32.1 using a silent polymorphism in the coding region.
Biochemical and biophysical research communications - 14 Sept 1995
Deckert J, Nöthen M M, Bryant S P, Ren H, Wolf H K, Stiles G L, Spurr N K, Propping P
Abstract excerpt
Adenosine is a major inhibitory neuromodulator in the central nervous system. One of the receptors mediating the central effects of adenosine is the adenosine A1 receptor. We performed a systematic mutation scan of the coding region of the adenosine A1 receptor gene to explore its variability in...
Topics
- Adult
- Animals
- Base Sequence
- Brain
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- DNA Primers
- Genetic Linkage
- Genetic Markers
- Genetic Variation
- Genotype
- Guanine
- Hominidae
- Humans
- Molecular Sequence Data