Article
Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort.
Psychiatric genetics - 1 Oct 2009
McAuley Erica Z, Fullerton Janice M, Blair Ian P, Donald Jennifer A, Mitchell Philip B, Schofield Peter R
Abstract excerpt
OBJECTIVE: The serotonin 2A receptor gene (HTR2A) is involved in serotonergic neurotransmission, and has been targeted as a functional candidate for mood disorders because of the extensive support for the involvement of serotonin in mood regulation. We previously reported linkage evidence for a bipolar affective disorder susceptibility locus on chromosome 13q, which harbours HTR2A, thus making the gene both a...
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