Article
Human adenosine A2a receptor (A2aAR) gene: systematic mutation screening in patients with schizophrenia.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 1996
Deckert J, Nöthen M M, Rietschel M, Wildenauer D, Bondy B, Ertl M A, Knapp M, Schofield P R, Albus M, Maier W, Propping P
Abstract excerpt
Several lines of evidence suggest an involvement of adenosine A2a receptor (A2aAR) mediated adenosinergic neuromodulation in the etiopathogenesis of schizophrenia. We therefore performed a systematic mutation scan of the complete coding region of the human A2aAR gene in a sample of 42 schizophren...
Topics
- Alleles
- Case-Control Studies
- Genetic Testing
- Genetic Variation
- Genotype
- Humans
- Mutation
- Pedigree
- Polymorphism, Single-Stranded Conformational
- Receptors, Purinergic P1
- Schizophrenia
- Sequence Analysis, DNA