Article
Systematic mutation screening and association study of the A1 and A2a adenosine receptor genes in panic disorder suggest a contribution of the A2a gene to the development of disease.
Molecular psychiatry - 1 Jan 1998
Deckert J, Nöthen M M, Franke P, Delmo C, Fritze J, Knapp M, Maier W, Beckmann H, Propping P
Abstract excerpt
Several lines of evidence suggest a contribution of adenosinergic neurotransmission to the development of panic disorder. We therefore hypothesized that variation in the A1 and A2a adenosine receptor (AR) genes modifies genetic susceptibility to panic disorder. To test this hypothesis, we screened 38 patients with panic disorder for mutations in the coding sequence of the A1AR and A2aAR genes. An association...
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