Article
A European multicenter association study of HTR2A receptor polymorphism in bipolar affective disorder.
American journal of medical genetics - 3 Apr 2000
Massat I, Souery D, Lipp O, Blairy S, Papadimitriou G, Dikeos D, Ackenheil M, Fuchshuber S, Hilger C, Kaneva R, Milanova V, Verheyen G, Raeymaekers P, Staner L, Oruc L, Jakovljevic M, Serretti A, Macciardi F, Van Broeckhoven C, Mendlewicz J
Abstract excerpt
The available data on the role of 5-HT in a variety of behaviors support the hypothesis that a dysfunction in brain serotoninergic system activity contributes to vulnerability to major depression. The diversity in the electrophysiological actions of 5-HT in the central nervous system can now be categorized according to receptor subtypes and their respective effector mechanisms. In particular, the implication of...
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