Article
Rapid haplotyping of mutations in the Duffy gene using the polymerase chain reaction and sequence-specific primers.
Tissue antigens - 1 Feb 1998
Mullighan C G, Marshall S E, Fanning G C, Briggs D C, Welsh K I
Abstract excerpt
The molecular basis for the antigenic variation and red cell expression of the Duffy antigen system has recently been elucidated. We have developed a simple one-step method for genotyping the single nucleotide polymorphisms in the promoter and exon of the Duffy gene using the polymerase chain rea...
Topics
- Alleles
- Antigenic Variation
- Base Sequence
- Black People
- DNA Primers
- Duffy Blood-Group System
- Erythrocytes
- Exons
- Gene Frequency
- Haplotypes
- Humans
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Promoter Regions, Genetic
- White People