Article
Determination of Duffy genotypes in three populations of African descent using PCR and sequence-specific oligonucleotides.
Human immunology - 1 Aug 1999
Nickel R G, Willadsen S A, Freidhoff L R, Huang S K, Caraballo L, Naidu R P, Levett P, Blumenthal M, Banks-Schlegel S, Bleecker E, Beaty T, Ober C, Barnes K C
Abstract excerpt
The expression of the Duffy Antigen/Receptor for Chemokines (DARC) on red blood cells (RBC) has been commonly determined using hemagglutination tests. Because the vast majority of African individuals are Duffy-negative, screening for DARC expression on RBC is a valuable tool to assess Caucasian admixture in populations of African descent. Furthermore, blood group antigens have been frequently tested as potential...
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