Article
Real-time multiplex allele-specific polymerase chain reaction for genotyping of the Duffy antigen, the Plasmodium vivax invasion receptor.
Vox sanguinis - 1 May 2007
Sousa T N, Sanchez B A M, Cerávolo I P, Carvalho L H, Brito C F A
Abstract excerpt
BACKGROUND AND OBJECTIVES: Duffy blood group is of major interest in clinical medicine as it is not only involved in blood-transfusion risks and occasionally in neonatal haemolytic disease, but it is also the receptor for the human malaria parasite Plasmodium vivax in the erythrocyte invasion. The aim of this study was to develop a rapid and inexpensive approach for high-throughput Duffy genotyping. MATERIALS AND...
Topics
- Alleles
- Animals
- Base Sequence
- Benzothiazoles
- DNA Primers
- Diamines
- Duffy Blood-Group System
- Erythrocytes
- Fluorescent Dyes
- Genotype
- Humans