Article
Molecular basis of the Duffy blood group system.
Blood transfusion = Trasfusione del sangue - 1 Jan 2018
Höher Gabriela, Fiegenbaum Marilu, Almeida Silvana
Abstract excerpt
ACKR1, located on chromosome 1q23.2, is the gene that encodes a glycoprotein expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants yielding two isoforms, encoding proteins with 338 and 336 amino acids. This review provides a general overview of the Duffy blood group to characterise and elucidate the genetic basis of this system. The Fya and Fyb antigens are encoded by...
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