Molecular basis of the Duffy blood group system.

doi:10.2450/2017.0119-16

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Article

Molecular basis of the Duffy blood group system.

Blood transfusion = Trasfusione del sangue - 1 Jan 2018

Höher Gabriela, Fiegenbaum Marilu, Almeida Silvana

Abstract excerpt

ACKR1, located on chromosome 1q23.2, is the gene that encodes a glycoprotein expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants yielding two isoforms, encoding proteins with 338 and 336 amino acids. This review provides a general overview of the Duffy blood group to characterise and elucidate the genetic basis of this system. The Fya and Fyb antigens are encoded by...

Topics

Alleles
Chromosomes, Human, Pair 1
Duffy Blood-Group System
Gene Expression Regulation
Homozygote
Humans
Point Mutation

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Open in PubMed Open full text

Identifiers

PMID: 28151395
DOI: 10.2450/2017.0119-16
PMCID: PMC5770319

Genes

ACKR1

Variants

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