Article
Dinucleotide repeat in the 3' flanking region provides a clue to the molecular evolution of the Duffy gene.
Human genetics - 1 May 1997
Li J, Iwamoto S, Sugimoto N, Okuda H, Kajii E
Abstract excerpt
The Duffy blood group system consists of three alleles, FYA, FYB, and FY. To study the molecular evolution of the three alleles, we established the polymorphism of a dinucleotide (GT) repeat sequence (designated FyGT/C) in the 3' flanking region of the Duffy gene, and studied the relationship between FyGT/C and Duffy polymorphism in Japanese, people of African origin, and chimpanzee. By single-strand conformation...
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