Article
Prenatal genotyping of the Duffy blood group system by allele-specific polymerase chain reaction.
Prenatal diagnosis - 1 Jan 1999
Hessner M J, Pircon R A, Johnson S T, Luhm R A
Abstract excerpt
Maternal allo-immunization to antigens of the Duffy blood group system can result in haemolytic disease of the newborn (HDN), therefore, the application of allele-specific polymerase chain reaction (ASPCR) for prenatal genotyping of the Duffy antigen system to identify pregnancies at risk for HDN was evaluated. Oligonucleotide primers were designed for ASPCR of FYA, FYB and nullFY alleles. A validation study was...
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