Mapping of a new target region of allelic loss to a 2-cM interval at 22q13.1 in primary breast cancer.

Article

Mapping of a new target region of allelic loss to a 2-cM interval at 22q13.1 in primary breast cancer.

Genes, chromosomes & cancer - 1 Feb 1998

Iida A, Kurose K, Isobe R, Akiyama F, Sakamoto G, Yoshimoto M, Kasumi F, Nakamura Y, Emi M

Abstract excerpt

Allelic losses on chromosome arm 22q are frequently observed in human meningiomas and in carcinomas of the colon, ovary, and breast. Among 140 primary breast cancers we examined for loss of heterozygosity (LOH) at 16 polymorphic loci on the long arm of chromosome 22, 56 (40%) showed LOH for at le...

Topics

Alleles
Breast Neoplasms
Chromosome Mapping
Chromosomes, Human, Pair 22
DNA, Neoplasm
Genes, Tumor Suppressor
Humans
Loss of Heterozygosity
Microsatellite Repeats

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