Article
Goosecoid misexpression alters the morphology and Hox gene expression of the developing chick limb bud.
Mechanisms of development - 1 Dec 1997
Heanue T A, Johnson R L, Izpisua-Belmonte J C, Stern C D, De Robertis E M, Tabin C J
Abstract excerpt
The homeobox-containing gene goosecoid (gsc) has been implicated in a variety of embryonic processes from gastrulation to rib patterning. We have analyzed the role it plays during chick limb development. Expression is initially observed at stage 20 in a proximal-anterior-ventral domain of the ear...
Topics
- Animals
- Cartilage
- Chick Embryo
- DNA-Binding Proteins
- Down-Regulation
- Femur
- Gene Expression Regulation, Developmental
- Goosecoid Protein
- Homeodomain Proteins
- Limb Buds
- Phenotype
- Repressor Proteins
- Retroviridae
- Transcription Factors