Article
Goosecoid misexpression alters the morphology and Hox gene expression of the developing chick limb bud.
Mechanisms of development - 1 Dec 1997
Heanue T A, Johnson R L, Izpisua-Belmonte J C, Stern C D, De Robertis E M, Tabin C J
Abstract excerpt
The homeobox-containing gene goosecoid (gsc) has been implicated in a variety of embryonic processes from gastrulation to rib patterning. We have analyzed the role it plays during chick limb development. Expression is initially observed at stage 20 in a proximal-anterior-ventral domain of the early limb bud which expands during subsequent stages. Later in limb development a second domain of expression appears...
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