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Article

Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b.

Development (Cambridge, England) - 1 May 2009

Dixon Fox Monica, Bruce Ashley E E

Abstract excerpt

The organizer is essential for dorsal-ventral (DV) patterning in vertebrates. Goosecoid (Gsc), a transcriptional repressor found in the organizer, elicits partial secondary axes when expressed ventrally in Xenopus, similar to an organizer transplant. Although gsc is expressed in all vertebrate organizers examined, knockout studies in mouse suggested that it is not required for DV patterning. Moreover, experiments...

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Identifiers

PMID: 19369398
DOI: 10.1242/dev.031161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b.PMID 19369398Read ↗

Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.Semantic proximity Read ↗

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Drosophila goosecoid participates in neural development but not in body axis formation.Semantic proximity Read ↗

The role of the homeodomain protein Bozozok in zebrafish axis formation.Semantic proximity Read ↗

Goosecoid expression in neurectoderm and mesendoderm is disrupted in zebrafish cyclops gastrulas.Semantic proximity Read ↗

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Patterning the zebrafish axial skeleton requires early chordin function.Semantic proximity Read ↗

Nodal/Bozozok-independent induction of the dorsal organizer by zebrafish cell lines.Semantic proximity Read ↗

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