Article
Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo.
Developmental genetics - 1 Jan 1995
Gasca S, Hill D P, Klingensmith J, Rossant J
Abstract excerpt
We have used a gene trap (GT) vector and embryonic stem (ES) cell chimeras to screen for insertions of the lacZ reporter gene into transcription units that are spatially and temporally regulated during early mouse embryogenesis. GT vectors which can act as both a reporter and a mutagen have been...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Chimera
- Chromosome Mapping
- Cloning, Molecular
- Cytoskeletal Proteins
- DNA Primers
- Embryonic and Fetal Development
- Female
- Gastrula
- Gene Expression Regulation, Developmental
- Genes, Reporter
- Genetic Vectors
- Lac Operon
- Male
- Mice