Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.

doi:10.1242/dev.121.9.3005

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Article

Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.

Development (Cambridge, England) - 1 Sept 1995

Rivera-Pérez J A, Mallo M, Gendron-Maguire M, Gridley T, Behringer R R

Abstract excerpt

Goosecoid (gsc) is an evolutionarily conserved homeobox gene expressed in the gastrula organizer region of a variety of vertebrate embryos, including zebrafish, Xenopus, chicken and mouse. To understand the role of gsc during mouse embryogenesis, we generated gsc-null mice by gene targeting in em...

Topics

Animals
DNA-Binding Proteins
Facial Bones
Female
Fetal Death
Gastrula
Gene Expression
Gene Targeting
Genes, Homeobox
Goosecoid Protein
Homeodomain Proteins
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Mutant Strains

Morphogenesis

Phenotype

Repressor Proteins

Ribs

Skull

Source

Open in PubMed

Identifiers

PMID: 7555726
DOI: 10.1242/dev.121.9.3005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7555726-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.PMID 7555726Read ↗

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