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Article

Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.

Development (Cambridge, England) - 1 Sept 1995

Rivera-Pérez J A, Mallo M, Gendron-Maguire M, Gridley T, Behringer R R

Abstract excerpt

Goosecoid (gsc) is an evolutionarily conserved homeobox gene expressed in the gastrula organizer region of a variety of vertebrate embryos, including zebrafish, Xenopus, chicken and mouse. To understand the role of gsc during mouse embryogenesis, we generated gsc-null mice by gene targeting in embryonic stem cells. Surprisingly, gsc-null embryos gastrulated and formed the primary body axes; gsc-null mice were...

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PMID: 7555726
DOI: 10.1242/dev.121.9.3005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.PMID 7555726Read ↗

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