Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants.

Mechanisms of development - 1 Mar 1998

Belo J A, Leyns L, Yamada G, De Robertis E M

Abstract excerpt

Gsc-1 expression marks cells with Spemann organizer, or axis-inducing, activity in the vertebrate gastrula. Gsc-1 knockouts, however, did not display phenotypes related to the early phase of expression. In this paper, additional phenotypes for the Gsc-1 mouse mutant are presented. Examination of the base of the cranium in the dorsal view revealed fusions and deletions in the midline of the prechordal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to DNA-Binding Proteins
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Molecular Sequence Data

Share to Phenotype

Share to Transcription Factors

Source

Identifiers

PMID: 9533949
DOI: 10.1016/s0925-4773(97)00204-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants.PMID 9533949Read ↗

Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.Semantic proximity Read ↗

Genetics of craniofacial development and malformation.Semantic proximity Read ↗

Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death.Semantic proximity Read ↗

SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid.Semantic proximity Read ↗

Gnas Loss Causes Chondrocyte Fate Conversion in Cranial Suture FormationSemantic proximity Read ↗

Mutations affecting development of the midline and general body shape during zebrafish embryogenesis.Semantic proximity Read ↗

Nasal and pharyngeal abnormalities caused by the mouse goosecoid gene mutation.Semantic proximity Read ↗

Craniofacial skeletal defects of adult zebrafish Glypican 4 (knypek) mutants.Semantic proximity Read ↗

Middle ear defects associated with the double knock out mutation of murine goosecoid and Msx1 genes.Semantic proximity Read ↗

Requirement for Dlgh-1 in planar cell polarity and skeletogenesis during vertebrate development.Semantic proximity Read ↗

Mouse mutant "rib-vertebrae" (rv): a defect in somite polarity.Semantic proximity Read ↗

SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.