Article
The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants.
Mechanisms of development - 1 Mar 1998
Belo J A, Leyns L, Yamada G, De Robertis E M
Abstract excerpt
Gsc-1 expression marks cells with Spemann organizer, or axis-inducing, activity in the vertebrate gastrula. Gsc-1 knockouts, however, did not display phenotypes related to the early phase of expression. In this paper, additional phenotypes for the Gsc-1 mouse mutant are presented. Examination of...
Topics
- Amino Acid Sequence
- Animals
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Fetal Proteins
- Genotype
- Goosecoid Protein
- Homeodomain Proteins
- Mesoderm
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Molecular Sequence Data
- Phenotype
- Repressor Proteins
- Skull
- T-Box Domain Proteins
- Transcription Factors