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Article

Searching for substitution rate heterogeneity.

Molecular phylogenetics and evolution - 1 Feb 1998

Hartmann M, Golding G B

Abstract excerpt

A permutation method for detecting regional substitution rate heterogeneity in DNA sequences is described. An estimated phylogeny for the sequences is required. The method is likelihood based and searches through all regions of a DNA sequence to find any regions that have an unusually large (or small) number of substitutions in comparison to an optimal substitution rate for the entire sequence. Likelihood ratio...

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PMID: 9479695
DOI: 10.1006/mpev.1997.0446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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