Article
Searching for substitution rate heterogeneity.
Molecular phylogenetics and evolution - 1 Feb 1998
Hartmann M, Golding G B
Abstract excerpt
A permutation method for detecting regional substitution rate heterogeneity in DNA sequences is described. An estimated phylogeny for the sequences is required. The method is likelihood based and searches through all regions of a DNA sequence to find any regions that have an unusually large (or s...
Topics
- Algorithms
- Computational Biology
- Computer Simulation
- Evolution, Molecular
- Genes, Plant
- Genetic Variation
- Likelihood Functions
- Phylogeny
- Sequence Analysis, DNA