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Article

Detecting substitution-rate heterogeneity among regions of a nucleotide sequence.

Molecular biology and evolution - 1 Jul 1994

Gaut B S, Weir B S

Abstract excerpt

Likelihood-ratio statistics are proposed to test for heterogeneity in nucleotide substitution rate among regions of a DNA sequence. The tests examine three-sequence phylogenies, and two specific tests are proposed: a test to detect rate heterogeneity among genic regions within a sequence, over all evolutionary lineages; and a test to detect rate heterogeneity among regions in a specific evolutionary lineage....

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PMID: 8078401
DOI: 10.1093/oxfordjournals.molbev.a040141

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