Article
Detecting substitution-rate heterogeneity among regions of a nucleotide sequence.
Molecular biology and evolution - 1 Jul 1994
Gaut B S, Weir B S
Abstract excerpt
Likelihood-ratio statistics are proposed to test for heterogeneity in nucleotide substitution rate among regions of a DNA sequence. The tests examine three-sequence phylogenies, and two specific tests are proposed: a test to detect rate heterogeneity among genic regions within a sequence, over all evolutionary lineages; and a test to detect rate heterogeneity among regions in a specific evolutionary lineage....
Topics
- Animals
- Computer Simulation
- DNA Transposable Elements
- Genes, Insect
- Genetic Variation
- Insecta
- Likelihood Functions
- Models, Genetic
- Mutation
- Phylogeny
- Pseudogenes