Article
A simple method to detect the heterogeneity of nucleotide substitution processes by measuring asymmetry in paired comparison.
Yi chuan xue bao = Acta genetica Sinica - 1 Oct 2005
Huang Jiao-Long, Cao Zhi-Qi, Zhang Ze, Zhu Da-Hai
Abstract excerpt
A simple method is presented, which uses a chi2 statistic to measure asymmetry of the substitution matrix between two DNA sequences in order to test a homogeneity hypothesis of the substitution processes. In theory, this chi2 test holds irrespective of whether there is among-site (i) heterogeneity in substitution rates, (ii) correlation in evolutionary rates/models, and (iii) variation in substitution models....
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