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Article

Estimating the pattern of nucleotide substitution.

Journal of molecular evolution - 1 Jul 1994

Yang Z

Abstract excerpt

Knowledge of the pattern of nucleotide substitution is important both to our understanding of molecular sequence evolution and to reliable estimation of phylogenetic relationships. The method of parsimony analysis, which has been used to estimate substitution patterns in real sequences, has serious drawbacks and leads to results difficult to interpret. In this paper a model-based maximum likelihood approach is...

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Identifiers

PMID: 8064867
DOI: 10.1007/BF00178256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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