Article
Testing substitution models within a phylogenetic tree.
Molecular biology and evolution - 1 Apr 2003
Weiss Gunter, von Haeseler Arndt
Abstract excerpt
Phylogenetic tree reconstruction frequently assumes the homogeneity of the substitution process over the whole tree. To test this assumption statistically, we propose a test based on the sample covariance matrix of the set of substitution rate matrices estimated from pairwise sequence comparison. The sample covariance matrix is condensed into a one-dimensional test statistic Delta = sum ln(1 + delta(i)), where...
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