Article
Detecting heterogeneity of substitution along DNA and protein sequences.
Genetics - 1 May 1996
Goss P J, Lewontin R C
Abstract excerpt
Regions of differing constraint, mutation rate or combination along a sequence of DNA or amino acids lead to a nonuniform distribution of polymorphism within species or fixed differences between species. The power of five tests to reject the null hypothesis of a uniform distribution is studied fo...
Topics
- Biological Evolution
- DNA
- Heterozygote
- Models, Genetic
- Monte Carlo Method
- Mutation
- Phylogeny
- Polymorphism, Genetic
- Probability
- Proteins
- Recombination, Genetic
- Software