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Article

Detecting heterogeneity of substitution along DNA and protein sequences.

Genetics - 1 May 1996

Goss P J, Lewontin R C

Abstract excerpt

Regions of differing constraint, mutation rate or combination along a sequence of DNA or amino acids lead to a nonuniform distribution of polymorphism within species or fixed differences between species. The power of five tests to reject the null hypothesis of a uniform distribution is studied for four classes of alternate hypothesis. The tests explored are the variance of interval lengths; a modified variance...

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Identifiers

PMID: 8722807
DOI: 10.1093/genetics/143.1.589
PMCID: PMC1207291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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