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Article

Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium.

Genetic epidemiology - 1 Jan 2002

Pfeiffer Ruth M, Rutter Joni L, Gail Mitchell H, Struewing Jeffery, Gastwirth Joseph L

Abstract excerpt

Pooling DNA samples can yield efficient estimates of the prevalence of genetic variants. We extend methods of analyzing pooled DNA samples to estimate the joint prevalence of variants at two or more loci. If one has a sample from the general population, one can adapt the method for joint prevalen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11754476
DOI: 10.1002/gepi.1046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11754476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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