Evidence for independent mismatch repair processing on opposite sides of a double-strand break in Saccharomyces cerevisiae.

doi:10.1093/genetics/148.1.59

Back to search

Article

Evidence for independent mismatch repair processing on opposite sides of a double-strand break in Saccharomyces cerevisiae.

Genetics - 1 Jan 1998

Weng Y S, Nickoloff J A

Abstract excerpt

Double-strand break (DSB) induced gene conversion in Saccharomyces cerevisiae during meiosis and MAT switching is mediated primarily by mismatch repair of heteroduplex DNA (hDNA). We used nontandem ura3 duplications containing palindromic frameshift insertion mutations near an HO nuclease recogni...

Topics

Alleles
DNA Damage
DNA Repair
DNA, Fungal
Frameshift Mutation
Fungal Proteins
Genetic Markers
Nucleic Acid Heteroduplexes
Saccharomyces cerevisiae

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.