Article
Multiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast.
Genetics - 1 Oct 1999
Nickoloff J A, Sweetser D B, Clikeman J A, Khalsa G J, Wheeler S L
Abstract excerpt
Spontaneous and double-strand break (DSB)-induced allelic recombination in yeast was investigated in crosses between ura3 heteroalleles inactivated by an HO site and a +1 frameshift mutation, with flanking markers defining a 3.4-kbp interval. In some crosses, nine additional phenotypically silent RFLP mutations were present at approximately 100-bp intervals. Increasing heterology from 0.2 to 1% in this interval...
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