Article
Reduced mismatch repair of heteroduplexes reveals "non"-interfering crossing over in wild-type Saccharomyces cerevisiae.
Genetics - 1 Mar 2008
Getz Tony J, Banse Stephen A, Young Lisa S, Banse Allison V, Swanson Johanna, Wang Grace M, Browne Barclay L, Foss Henriette M, Stahl Franklin W
Abstract excerpt
Using small palindromes to monitor meiotic double-strand-break-repair (DSBr) events, we demonstrate that two distinct classes of crossovers occur during meiosis in wild-type yeast. We found that crossovers accompanying 5:3 segregation of a palindrome show no conventional (i.e., positive) interference, while crossovers with 6:2 or normal 4:4 segregation for the same palindrome, in the same cross, do manifest...
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