Article
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae.
Genetics - 1 May 1994
Alani E, Reenan R A, Kolodner R D
Abstract excerpt
The yeast Saccharomyces cerevisiae encodes a set of genes that show strong amino acid sequence similarity to MutS and MutL, proteins required for mismatch repair in Escherichia coli. We examined the role of MSH2 and PMS1, yeast homologs of mutS and mutL, respectively, in the repair of base pair m...
Topics
- DNA Repair
- Epistasis, Genetic
- Mutation
- Nucleic Acid Heteroduplexes
- Phenotype
- Recombination, Genetic
- Saccharomyces cerevisiae