Article
GC-biased gene conversion in yeast is specifically associated with crossovers: molecular mechanisms and evolutionary significance.
Molecular biology and evolution - 1 Jun 2013
Lesecque Yann, Mouchiroud Dominique, Duret Laurent
Abstract excerpt
GC-biased gene conversion (gBGC) is a process associated with recombination that favors the transmission of GC alleles over AT alleles during meiosis. gBGC plays a major role in genome evolution in many eukaryotes. However, the molecular mechanisms of gBGC are still unknown. Different steps of the recombination process could potentially cause gBGC: the formation of double-strand breaks (DSBs), the invasion of the...
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