Double-strand break-induced mitotic gene conversion: examination of tract polarity and products of multiple recombinational repair events.

doi:10.1007/BF02208614

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Double-strand break-induced mitotic gene conversion: examination of tract polarity and products of multiple recombinational repair events.

Current genetics - 1 Mar 1996

Weng Y S, Whelden J, Gunn L, Nickoloff J A

Abstract excerpt

Double-strand break (DSB)-induced gene conversion in yeast was studied in crosses between ura3 heteroalleles carrying phenotypically silent markers at approximately 100-bp intervals, which allow high-resolution analyses of tract structures. DSBs were introduced in vivo by HO nuclease at sites within shared homology and were repaired using information donated by unbroken alleles. Previous studies with these types...

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Double-strand break-induced mitotic gene conversion: examination of tract polarity and products of multiple recombinational repair events.

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Double-strand break-induced mitotic gene conversion: examination of tract polarity and products of multiple recombinational repair events.

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