Article
Mismatch repair-induced meiotic recombination requires the pms1 gene product.
Genetics - 1 Mar 1990
Borts R H, Leung W Y, Kramer W, Kramer B, Williamson M, Fogel S, Haber J E
Abstract excerpt
The presence of multiple heterologies in a 9-kilobase (kb) interval results in a decrease in meiotic crossovers from 26.0% to 10.1%. There is also an increase from 3.5% to 11.1% in gene conversions and ectopic recombinations between the flanking homologous MAT loci. The hypothesis that mismatch repair of heteroduplex DNA containing several heterologies would lead to a second round of recombination has now been...
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