Mismatch repair-induced meiotic recombination requires the pms1 gene product.

doi:10.1093/genetics/124.3.573

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Article

Mismatch repair-induced meiotic recombination requires the pms1 gene product.

Genetics - 1 Mar 1990

Borts R H, Leung W Y, Kramer W, Kramer B, Williamson M, Fogel S, Haber J E

Abstract excerpt

The presence of multiple heterologies in a 9-kilobase (kb) interval results in a decrease in meiotic crossovers from 26.0% to 10.1%. There is also an increase from 3.5% to 11.1% in gene conversions and ectopic recombinations between the flanking homologous MAT loci. The hypothesis that mismatch r...

Topics

Alleles
DNA Repair
DNA, Fungal
Gene Expression
Genes, Fungal
Genotype
Mutation
Nucleic Acid Heteroduplexes
Recombination, Genetic
Saccharomyces cerevisiae

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