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Article

Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae.

Genetics - 1 Aug 1998

Kirkpatrick D T, Dominska M, Petes T D

Abstract excerpt

Meiotic recombination in yeast is associated with heteroduplex formation. Heteroduplexes formed between nonidentical DNA strands contain DNA mismatches, and most DNA mismatches in wild-type strains are efficiently corrected. Although some patterns of mismatch correction result in non-Mendelian segregation of the heterozygous marker (gene conversion), one predicted pattern of correction (restoration-type repair)...

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Identifiers

PMID: 9691029
DOI: 10.1093/genetics/149.4.1693
PMCID: PMC1460284

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